Nutrients produced by microorganisms utilising primarily CO2 from the air, with the support of biotechnology
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Funding Description
Key Facts
- Programme / Call: Horizon Europe, Cluster 6 – Farm-to-Fork, single-stage call (HORIZON-CL6-2025-02)
- Topic Identifier: HORIZON-CL6-2025-02-FARM2FORK-14
- Type of Action: Innovation Action (IA) – TRL target 5-8
- Indicative EU Contribution per Project: €8-12 million (Commission guidance); maximum possible: €50 million
- Funding Rate: 70 % of eligible direct costs (non-profit entities may receive 100 %) + 25 % flat-rate for indirect costs
- Opening / Deadline: 6 May 2025 → 16 Sept 2025, 17:00 CET (single-stage)
- Mandatory Consortium: ≥3 independent legal entities from ≥3 different EU Member States/Associated Countries, each established in a different country. Multi-actor approach requires meaningful involvement of: • SMEs & start-ups • Industrial food producers • Living labs/pilot plants • Academia/RTOs • Civil society & public authorities.
What Will Be Funded?
1. Biotechnology scale-up activities – design, construction or upgrading of pilot/demo bioreactors using engineered microbes that fix CO₂ (and potentially other gases) into food-grade nutrients (proteins, fats, enzymes, specialty ingredients).
2. Cost & investment analyses – CAPEX/OPEX modelling, techno-economic assessment, LCA and climate impact quantification.
3. Open digital platform – interoperable, EOSC-ready database/business-model toolbox for precision-fermentation actors.
4. Business models & go-to-market pilots – living-lab testing in industrial plants, assessment of on-site gas capture scenarios; replication roadmaps for SMEs across EU regions, with links to RIV4BFS.
5. Sustainability & resilience evaluation – cradle-to-gate LCA, circularity metrics, socio-economic analysis, One-Health & food-safety compliance.
6. Coordination & networking – dedicated task to work with parallel funded projects, international cooperation (esp. US), use of EU research infrastructures (e.g., IBISBA).
Eligibility Highlights
- Admissibility: 45-page limit (Part B), multi-actor approach statement required.
- Geographical eligibility: All MS & HE-associated countries automatically funded; other countries need own funds.
- Ethics & Regulatory: GMO/novel food compliance, biosafety, traceability, REACH/food contact materials where applicable.
Budget Structure Expectations (illustrative)
- 45 % – TRL advancement & pilot plant CAPEX/OPEX.
- 20 % – Digital platform & data governance.
- 15 % – Business modelling, living-lab operations, RIV integration.
- 10 % – Sustainability/LCA, climate impact, SS&H analyses.
- 10 % – Project management, networking, dissemination, exploitation & IP.
Tip: Reserve ≥3-5 % of budget for collaboration tasks and RIV4BFS alignment, as explicitly requested.
🇪🇸Spain Overview
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Related Opportunities for Spain
Enhancing plant protein production to bolster the resilience of agricultural systems and EU self-sufficiency in plant protein used as feed
Raising citizen awareness on alternative proteins derived from biotechnology
Scaling-up nutritional proteins from alternative sources
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