Biotech for Climate Resilient Crops and Plant-Based Biomanufacturing
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See in 5 min if you're eligible for Biotech for Climate Resilient Crops and Plant-Based Biomanufacturing offering max €120.0M funding💰 Funding Details
Biotech for Climate Resilient Crops and Plant-Based Biomanufacturing
Call Identifier: HORIZON-EIC-2025-PATHFINDERCHALLENGES-01-01
Type of Action: HORIZON Lump Sum Grant (EIC Pathfinder Challenge)
Planned Opening Date: 24 July 2025
Deadline: 29 October 2025 – 17:00 Brussels time
Maximum EU Contribution: up to €4 million per project (indicative), within an overall topic budget of €120 million
TRL Target at Project End: TRL 4 (validated in laboratory environment)
What the Grant Finances
* Breakthrough R&D that simultaneously (1) boosts climate-stress tolerance and resource-use efficiency *and* (2) increases nutritional value via native or non-native plant ingredients.
* Activities may include multi-omics analyses, AI-guided trait discovery, nanoparticle-enabled delivery systems, advanced genome editing, synthetic biology platforms, and plant/soil microbiome engineering.
* One mandatory consortium work package will harmonise monitoring, prediction and life-cycle assessment methodologies across all funded projects.
Eligible Applicants
* Single legal entities or consortia established in an EU Member State or Associated Country.
* Consortia of ≥2 entities must involve independent legal entities from ≥2 different countries; ≥3 entities must include at least one from an EU Member State and two from different Member States/Associated Countries.
* Mid-caps and large companies are *not* eligible for single-beneficiary applications.
Lump-Sum Specifics
* The EU contribution is paid as pre-agreed lump sums linked to work-package deliverables—no cost reporting. Robust work-plan structuring and internal cost realism are therefore essential.
Strategic Fit
This call underpins EU flagship policies: Green Deal, Farm-to-Fork, Mission Soil, Nature Restoration Law, Fit-for-55, REPowerEU and the 2024 Communication “Building the future with nature: Boosting Biotechnology and Biomanufacturing in the EU.”
📊 At a Glance
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🇪🇺 Strategic Advantages
EU-Wide Advantages & Opportunities for "Biotech for Climate Resilient Crops and Plant-Based Biomanufacturing"
1. Single Market Access
- 450 + million consumers, 27 Member States: Once a new climate-resilient variety or bio-ingredient is authorised at EU level, it can circulate freely under the Single Market principle (Art. 26 TFEU), multiplying commercial volumes without duplicate national registrations.
- Uniform seed & fertilising-product rules (Reg. (EU) 2019/1009, 2022/2379 on plant reproductive material) lower transaction costs and speed up go-to-market for stress-tolerant seeds or bio-fortified crops.
- Green Public Procurement & School Scheme give immediate demand anchors (EUR 1 bn/y fruit & veg budget) for nutrient-dense crops developed under the call.
2. Cross-Border Collaboration & Knowledge Exchange
- Geographical stress-gradient testing: Consortia can field-validate the same genotype from Mediterranean drought sites (ES, IT, EL) to Nordic photoperiod extremes (FI, SE), generating EU-wide performance data demanded by EFSA and CPVO.
- Shared research infrastructures: Access to pan-EU ESFRI assets such as
• ELIXIR & Euro-BioImaging for multi-omics pipelines;
• EMPHASIS plant phenotyping platforms;
• AnaEE field sites for soil–plant–microbiome experiments.
- Talent mobility schemes (Marie Skłodowska-Curie Actions, Erasmus Mundus) ease recruitment of highly specialised synthetic biologists and bioinformaticians across borders.
3. Alignment with Core EU Policies
- European Green Deal & Farm-to-Fork: Directly targets greener inputs, reduced pesticide/fertiliser use and healthier diets.
- Mission Soil: Generates data and practices that feed into the Mission’s Living Labs and monitors.
- Nature Restoration Law & Biodiversity Strategy 2030: Diversified stress-tolerant varieties help restore agro-ecosystem functions.
- REPowerEU & Fit-for-55: Plants that require less water/fertiliser cut energy demand for irrigation and ammonia synthesis, lowering GHGs.
4. Regulatory Harmonisation Advantages
- Single EFSA scientific opinion valid in all Member States for GM/NGT traits reduces regulatory duplication versus 27 separate national dossiers.
- Common variety registration & plant breeders’ rights (CPVO) shortens time-to-market.
- Upcoming EU legislative proposal on NGTs (expected 2025) may create an expedited path; Pathfinder results will be first-movers when the new framework enters into force.
5. Innovation Ecosystem Leverage
- EIC Continuum: Successful Pathfinder projects can fast-track into EIC Transition (up to €2.5 m) and EIC Accelerator (up to €15 m blended finance) without losing momentum.
- EIT Food KIC offers test farms, challenge labs and market-oriented acceleration for spin-offs.
- Circular Bio-based Europe JU (CBE) can fund pilot biorefineries converting plant biomass/ingredients to market-ready products.
- Access to European Innovation Hubs for AI & Robotics in AgriFood (Digital Europe) for phenotyping and precision breeding.
6. Funding Synergies & Stacking Options
- CAP Strategic Plans 2028–2034: Eco-schemes can reward farmers who adopt new climate-resilient varieties.
- LIFE Programme for large-scale demo of stress-tolerant crops in Natura 2000 areas.
- Interregional Innovation Investments (I3): co-fund cross-border value chains for plant-based proteins.
- European Investment Bank & InvestEU: debt/equity for first-of-a-kind biomanufacturing facilities.
7. Scale & Impact Potential at EU Level
- Protein autonomy: EU imports ~17 Mt soy/year; high-protein legumes developed under this call can replace up to 25 %, saving ~€4 bn trade deficit.
- Climate resilience: Doubling water-use efficiency could free 10 km³ of irrigation water annually—equivalent to the household consumption of 60 M EU citizens.
- Biodiversity uplift through wider crop portfolio (pulses, orphan crops) aligns with CAP Good Agricultural Practices and Eco-scheme criteria.
- Export leadership: Harmonised EU standards act as de-facto global benchmarks; successful technologies can be licensed worldwide, reinforcing EU biotech sovereignty.
8. Strategic Value of Operating at EU Scale
1. Economies of scope: pooling diverse germplasm, stress environments and consumer preferences impossible within a single Member State.
2. Risk sharing: Lump-sum model and cross-border consortia dilute scientific, regulatory and market risks.
3. Standardised LCA & climate-adaptation metrics: Joint work package on monitoring creates a European reference framework, easing future regulatory approvals and green-label certifications.
4. Policy influence: Multi-national consortia gain a stronger voice in shaping the upcoming NGT regulation and Sustainable Food Systems Framework Law.
9. Actionable Opportunities for Applicants
- Build tri-partite consortia (academia–SME–primary producer) from at least 3 Member/Associated States to exploit diverse test sites and maximise evaluation scores.
- Integrate AI-enabled phenomics with gene-editing to address the call’s emphasis on multi-omics and advanced AI.
- Plan for TRL-4 ➔ TRL-6 bridge by mapping EIC Transition/CBE JU calls in 2026-27.
- Engage early with EFSA & CPVO through pre-submission consultations to de-risk regulatory pathway.
- Leverage Horizon IP Scan & European IP Helpdesk to set up freedom-to-operate and joint-IP models suitable for cross-border commercialisation.
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Bottom line: Positioning your project at EU level unlocks unrivalled market size, regulatory efficiency, funding escalators and a continent-wide innovation network—advantages that no purely national scheme can match for delivering the next generation of climate-smart, nutrient-rich crops and plant-based biomanufacturing platforms.
🏷️ Keywords
Ready to Apply?
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See in 5 min if you're eligible for Biotech for Climate Resilient Crops and Plant-Based Biomanufacturing offering max €120.0M funding