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FORTHCOMING

Biotech for Climate Resilient Crops and Plant-Based Biomanufacturing

Last Updated: 8/19/2025Deadline: 28 October 2025€120.0M Available

Quick Facts

Programme:Horizon Europe
Call ID:HORIZON-EIC-2025-PATHFINDERCHALLENGES-01-01
Deadline:28 October 2025
Max funding:€120.0M
Status:
forthcoming
Time left:3 months

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💰 Funding Details

Biotech for Climate Resilient Crops and Plant-Based Biomanufacturing


Call Identifier: HORIZON-EIC-2025-PATHFINDERCHALLENGES-01-01

Type of Action: HORIZON Lump Sum Grant (EIC Pathfinder Challenge)

Planned Opening Date: 24 July 2025

Deadline: 29 October 2025 – 17:00 Brussels time

Maximum EU Contribution: up to €4 million per project (indicative), within an overall topic budget of €120 million

TRL Target at Project End: TRL 4 (validated in laboratory environment)


What the Grant Finances

* Breakthrough R&D that simultaneously (1) boosts climate-stress tolerance and resource-use efficiency *and* (2) increases nutritional value via native or non-native plant ingredients.

* Activities may include multi-omics analyses, AI-guided trait discovery, nanoparticle-enabled delivery systems, advanced genome editing, synthetic biology platforms, and plant/soil microbiome engineering.

* One mandatory consortium work package will harmonise monitoring, prediction and life-cycle assessment methodologies across all funded projects.


Eligible Applicants

* Single legal entities or consortia established in an EU Member State or Associated Country.

* Consortia of ≥2 entities must involve independent legal entities from ≥2 different countries; ≥3 entities must include at least one from an EU Member State and two from different Member States/Associated Countries.

* Mid-caps and large companies are *not* eligible for single-beneficiary applications.


Lump-Sum Specifics

* The EU contribution is paid as pre-agreed lump sums linked to work-package deliverables—no cost reporting. Robust work-plan structuring and internal cost realism are therefore essential.


Strategic Fit

This call underpins EU flagship policies: Green Deal, Farm-to-Fork, Mission Soil, Nature Restoration Law, Fit-for-55, REPowerEU and the 2024 Communication “Building the future with nature: Boosting Biotechnology and Biomanufacturing in the EU.”

Personalizing...

📊 At a Glance

€120.0M
Max funding
28 October 2025
Deadline
3 months
Time remaining
Eligible Countries
EU Member States, Associated Countries

🇪🇺 Strategic Advantages

EU-Wide Advantages & Opportunities for "Biotech for Climate Resilient Crops and Plant-Based Biomanufacturing"


1. Single Market Access

- 450 + million consumers, 27 Member States: Once a new climate-resilient variety or bio-ingredient is authorised at EU level, it can circulate freely under the Single Market principle (Art. 26 TFEU), multiplying commercial volumes without duplicate national registrations.

- Uniform seed & fertilising-product rules (Reg. (EU) 2019/1009, 2022/2379 on plant reproductive material) lower transaction costs and speed up go-to-market for stress-tolerant seeds or bio-fortified crops.

- Green Public Procurement & School Scheme give immediate demand anchors (EUR 1 bn/y fruit & veg budget) for nutrient-dense crops developed under the call.


2. Cross-Border Collaboration & Knowledge Exchange

- Geographical stress-gradient testing: Consortia can field-validate the same genotype from Mediterranean drought sites (ES, IT, EL) to Nordic photoperiod extremes (FI, SE), generating EU-wide performance data demanded by EFSA and CPVO.

- Shared research infrastructures: Access to pan-EU ESFRI assets such as

• ELIXIR & Euro-BioImaging for multi-omics pipelines;

• EMPHASIS plant phenotyping platforms;

• AnaEE field sites for soil–plant–microbiome experiments.

- Talent mobility schemes (Marie Skłodowska-Curie Actions, Erasmus Mundus) ease recruitment of highly specialised synthetic biologists and bioinformaticians across borders.


3. Alignment with Core EU Policies

- European Green Deal & Farm-to-Fork: Directly targets greener inputs, reduced pesticide/fertiliser use and healthier diets.

- Mission Soil: Generates data and practices that feed into the Mission’s Living Labs and monitors.

- Nature Restoration Law & Biodiversity Strategy 2030: Diversified stress-tolerant varieties help restore agro-ecosystem functions.

- REPowerEU & Fit-for-55: Plants that require less water/fertiliser cut energy demand for irrigation and ammonia synthesis, lowering GHGs.


4. Regulatory Harmonisation Advantages

- Single EFSA scientific opinion valid in all Member States for GM/NGT traits reduces regulatory duplication versus 27 separate national dossiers.

- Common variety registration & plant breeders’ rights (CPVO) shortens time-to-market.

- Upcoming EU legislative proposal on NGTs (expected 2025) may create an expedited path; Pathfinder results will be first-movers when the new framework enters into force.


5. Innovation Ecosystem Leverage

- EIC Continuum: Successful Pathfinder projects can fast-track into EIC Transition (up to €2.5 m) and EIC Accelerator (up to €15 m blended finance) without losing momentum.

- EIT Food KIC offers test farms, challenge labs and market-oriented acceleration for spin-offs.

- Circular Bio-based Europe JU (CBE) can fund pilot biorefineries converting plant biomass/ingredients to market-ready products.

- Access to European Innovation Hubs for AI & Robotics in AgriFood (Digital Europe) for phenotyping and precision breeding.


6. Funding Synergies & Stacking Options

- CAP Strategic Plans 2028–2034: Eco-schemes can reward farmers who adopt new climate-resilient varieties.

- LIFE Programme for large-scale demo of stress-tolerant crops in Natura 2000 areas.

- Interregional Innovation Investments (I3): co-fund cross-border value chains for plant-based proteins.

- European Investment Bank & InvestEU: debt/equity for first-of-a-kind biomanufacturing facilities.


7. Scale & Impact Potential at EU Level

- Protein autonomy: EU imports ~17 Mt soy/year; high-protein legumes developed under this call can replace up to 25 %, saving ~€4 bn trade deficit.

- Climate resilience: Doubling water-use efficiency could free 10 km³ of irrigation water annually—equivalent to the household consumption of 60 M EU citizens.

- Biodiversity uplift through wider crop portfolio (pulses, orphan crops) aligns with CAP Good Agricultural Practices and Eco-scheme criteria.

- Export leadership: Harmonised EU standards act as de-facto global benchmarks; successful technologies can be licensed worldwide, reinforcing EU biotech sovereignty.


8. Strategic Value of Operating at EU Scale

1. Economies of scope: pooling diverse germplasm, stress environments and consumer preferences impossible within a single Member State.

2. Risk sharing: Lump-sum model and cross-border consortia dilute scientific, regulatory and market risks.

3. Standardised LCA & climate-adaptation metrics: Joint work package on monitoring creates a European reference framework, easing future regulatory approvals and green-label certifications.

4. Policy influence: Multi-national consortia gain a stronger voice in shaping the upcoming NGT regulation and Sustainable Food Systems Framework Law.


9. Actionable Opportunities for Applicants

- Build tri-partite consortia (academia–SME–primary producer) from at least 3 Member/Associated States to exploit diverse test sites and maximise evaluation scores.

- Integrate AI-enabled phenomics with gene-editing to address the call’s emphasis on multi-omics and advanced AI.

- Plan for TRL-4 ➔ TRL-6 bridge by mapping EIC Transition/CBE JU calls in 2026-27.

- Engage early with EFSA & CPVO through pre-submission consultations to de-risk regulatory pathway.

- Leverage Horizon IP Scan & European IP Helpdesk to set up freedom-to-operate and joint-IP models suitable for cross-border commercialisation.


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Bottom line: Positioning your project at EU level unlocks unrivalled market size, regulatory efficiency, funding escalators and a continent-wide innovation network—advantages that no purely national scheme can match for delivering the next generation of climate-smart, nutrient-rich crops and plant-based biomanufacturing platforms.

🏷️ Keywords

Topic
Forthcoming