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OPEN

Bio-based drop-ins/smart drop-in platform chemicals, via cost-effective, sustainable and resource-efficient conversion of biomass

Last Updated: 8/19/2025Deadline: TBD€172.1M Available

Quick Facts

Programme:Horizon Europe
Call ID:HORIZON-JU-CBE-2025-IAFlag-02
Deadline:TBD
Max funding:€172.1M
Status:
open

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💰 Funding Details

Funding Description


Core Facts

* Programme: Horizon Europe – Circular Bio-based Europe Joint Undertaking (CBE-JU)

* Call Identifier: HORIZON-JU-CBE-2025-IAFlag-02

* Action Type: Innovation Action – *Flagship* (large-scale demo, TRL 8)

* Indicative EU Contribution per Grant: €172,137,258

* Funding Rate: Up to 60 % of eligible costs for for-profit partners, 100 % for non-profit entities (as per Horizon Europe rules for IAs).

* Stage: Single-stage submission

* Opening Date: 03 Apr 2025

Deadline: 18 Sep 2025, 17:00 Brussels time


Strategic Purpose

This flagship call underpins the EU Bioeconomy Strategy, Chemicals Strategy for Sustainability and Zero-Pollution Action Plan. It seeks to build a full-scale biorefinery that converts sustainable biomass into bio-based drop-in or smart drop-in platform chemicals, decreasing fossil dependence and reinforcing EU strategic autonomy.


Budget Logic

1. Scale-up CAPEX: Large demonstration assets, utilities integration, logistics & storage.

2. OPEX for validation: Feedstock sourcing, continuous 24/7 operation, product quality certification.

3. Downstream application (≥ TRL 6): Formulation, compounding, pilot product lines (e.g. bio-PET, bio-propylene glycol).

4. SSbD & Regulatory: Comprehensive Safe-and-Sustainable-by-Design studies, REACH dossiers, LCA/TEA.

5. Market Uptake & Replicability: Business modelling, offtake agreements, regional socio-economic assessment.


> Tip: Allocate ~5 % of the budget to robust project management, data management, communication & exploitation, as reviewers expect strong coordination for a flagship of this size.


Personalizing...

🇪🇺 Strategic Advantages

EU-Wide Advantages & Opportunities under HORIZON-JU-CBE-2025-IAFlag-02


1. Strategic Overview

The flagship topic “Bio-based drop-ins/smart drop-in platform chemicals, via cost-effective, sustainable and resource-efficient conversion of biomass” is purposely framed for pan-European deployment. Achieving TRL 8 for full-scale biorefineries and TRL 6+ for downstream products requires volumes of feedstock, capital, talent and markets that no single Member State can supply alone. Leveraging the EU’s regulatory, financial and scientific integration is therefore a fundamental success factor.


2. Single Market Access – 450+ Million Consumers & Industrial Off-takers

Immediate substitution potential: Drop-in molecules fit existing EU chemical value chains (polymers, solvents, surfactants, etc.), letting innovators sell directly into a unified market without reformulation hurdles.

Pan-EU feedstock sourcing: Uniform rules on waste & by-products (Waste Framework Directive, RED III) facilitate cross-border movement of secondary biomass, securing steady plant supply.

Economies of scale: A plant sized for the EU market (as opposed to national demand) achieves lower €/t CAPEX & OPEX, crucial for parity with fossil analogues.

Public procurement levers: Green Public Procurement criteria—and forthcoming mandatory bio-based content targets—apply EU-wide, generating predictable pull.


3. Cross-Border Collaboration & Value-Chain Integration

Transnational consortia can pool:

– Northern/Eastern forestry residues

– Mediterranean agro-wastes

– Western high-tech catalysts & process engineering

– Central EU polymer converters & brand owners.

• Knowledge exchange via CBE JU’s project portfolio (AFTERBIOCHEM, URBIOFIN, etc.) accelerates scale-up learning curves and plant optimisation.

Joint off-take agreements with multiple Member State customers de-risk investment and satisfy the topic’s Multi-Actor Approach (MAA).


4. Alignment with EU Policy Objectives

European Green Deal & Fit-for-55: Direct GHG reductions from fossil substitution support 55 % target and CBAM resilience.

EU Bioeconomy Strategy: Converts under-utilised biomass into high-value chemicals, boosting rural economies.

Chemicals Strategy for Sustainability (CSS): Safe-and-Sustainable-by-Design (SSbD) task positions companies ahead of upcoming REACH revisions.

Industrial Transition Pathway for Chemicals: Flagship status fits Priority Action 2 (renewable feedstocks) and Action 4 (first-of-a-kind plants).


5. Regulatory Harmonisation – A Competitive Edge

• One EU-wide REACH registration instead of 27 national dossiers lowers compliance costs.

• Mutual recognition of ESG and taxonomy criteria enables streamlined financing from EU green investors.

• Harmonised state-aid rules (Important Projects of Common European Interest – IPCEI) can stack with CBE funding for capex scale-up.


6. Access to the EU Innovation Ecosystem

European Technology Platforms (SusChem, Forest-Based Sector, etc.) provide ready-made networks for dissemination & recruitment.

• Synergies with Digital Europe and AI4EU can digitalise biorefinery operations (predictive maintenance, LCA automation).

• Proximity to world-class RTOs (Fraunhofer, VTT, TNO, CEA) and pilot infrastructures (Biorizon, BPF, ReSolute) shortens time to TRL 8.


7. Funding Synergies

Blend CBE JU grant with:

– Innovation Fund (for large CAPEX & OPEX support)

– EIB Green Loans / InvestEU guarantees

– Cohesion Policy & Modernisation Fund for regional deployment

– LIFE programme for downstream application demos.

• Sequencing example: Horizon Europe RIA ➜ this CBE JU IAFlag ➜ Innovation Fund for first commercial replication.


8. Scale & EU-Wide Impact Potential

Replication: Once first plant proves economics, identical modules can be rolled out near feedstock hubs in several Member States, multiplying impact.

Strategic Autonomy: EU-made drop-ins reduce dependence on imported naphtha/ethane; aligns with REPowerEU.

Export Leadership: Standardised SSbD data positions EU products for premium global markets that demand sustainability verification (e.g., Japan, California).


9. Socio-Economic Benefits Across Regions

Rural/industrial symbiosis: Valorisation of agricultural residues boosts farmer revenues and revitalises lagging regions.

High-quality jobs: Process engineers, data scientists, LCA specialists—talent distributed across Member States through consortium structure.

Just Transition: Repurposing of fossil refineries in carbon-intensive regions (e.g., lignite areas) mitigates social impacts of decarbonisation.


10. Actionable Tips for Applicants (EU-Scale Lens)

1. Map the full cross-border feedstock logistics chain and quantify security-of-supply benefits at EU level.

2. Integrate at least 3 Member State end-users to demonstrate Single Market uptake and satisfy MAA.

3. Build a regulatory work package that pre-screens REACH, CLP and endocrine disruptor criteria across the EU to evidence harmonisation advantages.

4. Set up a Joint Exploitation Board to coordinate post-project replication in other EU regions and align with cohesion funds.

5. Leverage existing EU demo assets (BBI JU pilots) to avoid duplicative CAPEX and strengthen value-for-money.


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Bottom line: Competing globally on cost-effective bio-based drop-in chemicals demands the combined market size, harmonised rules, R&D excellence and financial firepower unique to the European Union. The CBE JU flagship call is specifically structured to make these EU-wide advantages actionable and bankable for consortia that think beyond national borders.