Interregional Innovation Investments Strand 1
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See in 5 min if you're eligible for Interregional Innovation Investments Strand 1 offering max €23.0M funding💰 Funding Details
Interregional Innovation Investments Strand 1 (I3-2025-INV1)
Overview
The I3 Strand 1 action grant finances *interregional* investment portfolios that scale up mature innovations (minimum TRL 6) toward market uptake and commercialisation. The instrument is embedded in the European Regional Development Fund (ERDF) and supports Smart Specialisation (S3) priorities that strengthen EU value chains while closing the innovation gap between more developed, transition and less developed regions.
* Grant ceiling: €23 million per project (ERDF co-financing, budget-based MGA)
* Thematic priorities (choose one only):
- Digital transition
- Green transition
- Smart manufacturing
* Opening date: 22 May 2025
Deadline: 13 Nov 2025, 17:00 (Brussels)
* Consortium profile: Quadruple-helix ecosystems (private sector, academia/RTOs, public authorities, civil society) from at least three regions in three different your country belonging to at least two cohesion categories (*≥1 partner from a Less Developed Region is mandatory*).
Funding Scope
Eligible costs span tangible and intangible investments required to pilot, demonstrate and de-risk innovative solutions:
1. Pilot lines, test beds, large-scale product validation, certification.
2. Adaptation/upgrade of existing prototypes to client needs (no ex-novo basic research).
3. Business & investment planning, IPR, standardisation, regulatory alignment.
4. Cascade funding (FSTP) schemes to involve additional SMEs.
5. Advisory services accelerating go-to-market and access to blended finance (VC, EIB, PPP).
Expected Impact
* Short-term: solutions demonstrated, SMEs integrated into EU value chains, interregional co-investment pipelines created.
* Long-term: higher productivity, greener & more digital industry, reinforced EU strategic autonomy, territorial cohesion and job creation.
> Good to know: Proposals may build on results from Strand 2b projects, Horizon Europe, Interreg or Digital Europe, provided they now focus on investment-ready deployment.
📊 At a Glance
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🇪🇺 Strategic Advantages
EU-Wide Advantages & Opportunities of the “Interregional Innovation Investments – Strand 1” (I3-2025-INV1)
1. Single Market Access
- 450 + million consumers & 23 million SMEs: I3 allows pilots at TRL 6–8 to be demonstrated simultaneously in several Member States, accelerating time-to-market and pan-EU certification/standard adoption.
- Public-procurement leverage: Beneficiaries can tap into cross-border innovation-friendly procurement clauses (e.g., joint procurement under the Public Procurement Directive), enlarging initial reference markets beyond a single country.
- Free movement of data, goods and services: Especially relevant for Digital Transition investments (AI, cybersecurity, data spaces) where cross-border data flows are critical for business models.
2. Cross-Border Collaboration & Knowledge Exchange
- Quadruple-helix consortia: Mandatory involvement of business, research, government and civil society actors from at least three regions fosters multidisciplinary solutions and opens door to cluster-to-cluster agreements (e.g., EDIH network, S3 Thematic Platforms).
- Inclusion of Less Developed Regions (LDRs): Advantages for lead partners from more developed regions to access cost-competitive pilot sites, test-beds and skilled talent pools; LDRs gain entry into mature EU value chains and investment readiness coaching.
- Shared testbeds & demo facilities: Mutual access agreements reduce CAPEX by 20-40 % on average (EC Smart Specialisation Platform data) and speed up scaling.
3. Alignment with Flagship EU Policies
- European Green Deal & Clean Industrial Deal: Green Transition projects qualify for additional Green Taxonomy-aligned financing and simplified permitting under REPowerEU fast-track schemes.
- Digital Decade & Digital Europe Programme: Digital Transition investments can plug into existing European Data Spaces, Gaia-X nodes and rely on HPC capacities funded by EuroHPC.
- Strategic Technologies for Europe Platform (STEP, Reg. EU 2024/795): Projects in critical tech areas (AI, semiconductors, advanced materials, biotech) gain priority access to blended financing under InvestEU and the EIC Scale-up window.
4. Regulatory Harmonisation Benefits
- Single set of conformity assessments (CE-marking, MDR, CPR, etc.): One approval valid EU-wide reduces cost/time by up to 30 % compared with sequential national procedures.
- EU Cybersecurity Act & AI Act sandboxing: Projects can test compliance once and deploy across borders without re-certification.
5. Access to Europe’s Innovation Ecosystem
- 3,400+ Higher Education Institutions & 300+ EIT KIC partners: I3 can finance mobility, shared IP exploitation and joint spin-off creation.
- Digital Innovation Hubs (EDIHs) & Pilot Lines: Immediate routes for technology validation and SME onboarding, lowering TRL-to-MRL gap.
- S3 Community: 280+ regional S3 areas offer matchmaking events and databases to find complementary capabilities.
6. Funding Synergies & Financial Engineering
- Cascade Funding (FSTP): Up to €60 k per SME de-risking, complemented by regional ERDF vouchers.
- Blend with other EU instruments:
• Horizon Europe for upstream R&D (TRL 3-6).
• InvestEU & EIB loans for scale-up CAPEX (> €7.5 m).
• Innovation Fund for large decarbonisation pilots (> €7.5 m, 55 % GHG reduction).
• LIFE/CEF2 for green & mobility infrastructure plug-ins.
- State-Aid compatibility: I3 grants count as ERDF support; Guidelines on Regional Aid 2021–27 allow higher aid intensities (up to 50 % in LDRs).
7. EU-Level Scale & Impact Potential
- Critical mass for new value chains: Interregional investment portfolios can aggregate >€30 m in parallel sub-projects, achieving tipping-point demand for novel materials, green hydrogen hubs, or cross-border data platforms.
- Replication model: Mandatory exploitation plans facilitate roll-out via other S3 regions and Interreg programmes, maximising socio-economic spill-overs.
- Contribution to cohesion & resilience: By integrating LDRs, projects can reduce innovation divide indices (Regional Innovation Scoreboard) and strengthen EU strategic autonomy.
8. Practical Tips to Maximise EU-Wide Advantages
- Map complementary S3 priorities early: Use S3 Platform matchmaking tool to identify at least two LDR/TR regions sharing your thematic priority.
- Design investment portfolios around value-chain gaps: Include demo sites, skills programmes and downstream market replication work packages for a coherent TRL 6-9 pathway.
- Leverage existing EU facilities: Reference EDIHs, EIT labs, Euroclusters or European Testing & Experimentation Facilities (TEFs) to justify cost-effective access to infrastructure.
- Plan blended finance from day one: Attach letters of interest from EIB, regional promotional banks or venture funds to score higher on sustainability & scalability.
- Address EU regulatory roadmaps: Integrate conformity assessment, AI Act compliance, or Fit-for-55 standards into your work plan to show readiness for EU-wide deployment.
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Bottom-Line Advantage: Operating at EU scale through I3-2025-INV1 enables consortia to de-risk and accelerate commercialisation of mature innovations, tap larger unified markets, pool cross-border expertise, and align with flagship EU strategies—delivering impacts unattainable through purely national initiatives.
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Ready to Apply?
Get a personalized assessment of your eligibility and application strategy
See in 5 min if you're eligible for Interregional Innovation Investments Strand 1 offering max €23.0M funding