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Interregional Innovation Investments Strand 2a

Last Updated: 8/19/2025Deadline: 12 November 2025€24.0M Available

Quick Facts

Programme:Horizon Europe
Call ID:I3-2025-INV2
Deadline:12 November 2025
Max funding:€24.0M
Status:
open
Time left:3 months

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💰 Funding Details

Funding At A Glance


Budget Envelope

* Maximum EU contribution per project: €24 000 000 (I3-AG)

* Funding rate: up to 70 % of eligible costs (unless a higher rate is justified for non-profit entities or specific State-aid compliant measures)


Eligible Activities

1. Investment-ready sub-projects within an interregional portfolio (TRL ≥ 6)

2. Demonstration & large-scale validation in real environments

3. Cascade funding (FSTP) to SMEs in value-chain niches

4. Non-financial services: coaching, mentoring, matchmaking


Geographic Logic

* Consortia must include at least one partner from a Less Developed Region (LDR) and show *balanced* participation across development levels.

* Capitalise on your country Smart Specialisation priorities and cross-border complementarities.


Thematic Windows

* Digital transition – AI-driven solutions, cybersecurity, digital public services

* Green transition – decarbonisation, circular materials, renewable energy value chains

* Smart manufacturing – advanced materials, robotics, industrial symbiosis


Financial Engineering Tips

* Combine I3 funds with ERDF, InvestEU, EIB loans or regional venture capital to close residual financing gaps.

* Demonstrate a co-investment commitment from private actors (>25 % of total budget is viewed positively).


Personalizing...

📊 At a Glance

€24.0M
Max funding
12 November 2025
Deadline
3 months
Time remaining

🇪🇺 Strategic Advantages

EU-Wide Advantages & Opportunities of the I3-2025-INV2a Grant (Interregional Innovation Investments – Strand 2a)


1. Direct Access to the EU Single Market

450 + million consumers & 23 million firms: Projects stemming from Strand 2a enter a tariff-free, regulation-harmonised market that maximises addressable demand from day one.

Pan-European procurement: Successful demonstrators can bid for cross-border public contracts (eIDAS-enabled), accelerating commercial uptake in health, smart mobility, energy and e-government.

Fast-track mutual recognition: Products validated through I3 benefit from mutual recognition of standards and conformity assessments, reducing launch time and cost in multiple Member States.


2. Cross-Border Collaboration & Value-Chain Integration

Mandatory multi-regional consortia: The call requires balanced participation of less-developed (LDR), transition (TR) and more-developed regions, systematically embedding SMEs into trans-national value chains.

Complementary S3 assets: Partners match regional Smart Specialisation (S3) priorities, enabling joint exploitation of pilot lines, living labs, DIHs, EDIHs and test beds situated in different countries.

Knowledge spill-overs: Joint work packages on demonstration and market replication create codified know-how openly transferrable across borders, strengthening Europe-wide diffusion channels.


3. Alignment with Flagship EU Policies

European Green Deal / Clean Industrial Deal: Green transition projects can directly report on Fit-for-55 KPIs (GHG reduction, circularity, energy efficiency), facilitating future ERDF, CEF or Innovation Fund blending.

Europe Fit for the Digital Age: Digital transition investments dovetail with Digital Europe Programme, AI Act implementation and the EU Cybersecurity Strategy, ensuring policy coherence and additional financing avenues.

New European Innovation Agenda & STEP (Reg. 2024/795): Strand 2a explicitly references critical technologies lists, positioning beneficiaries for later STEP or Important Projects of Common European Interest (IPCEI) calls.


4. Regulatory Harmonisation & Standard-Setting Influence

Early compliance feedback: Consortia can interact with EU standardisation bodies (CEN-CENELEC, ETSI) during demonstration, shaping emerging norms for AI, advanced materials or hydrogen.

Reduced fragmentation risk: Single set of Horizon Model Grant Agreement rules plus ERDF cross-border eligibility removes national red tape and facilitates state-aid-compliant public–private partnerships (PPP).


5. Pan-European Innovation Ecosystem Access

Top RTOs & universities: I3 projects routinely involve Fraunhofer, CEA, TNO, VTT, SINTEF, etc., granting SMEs privileged entry to world-class labs and human capital.

EU platforms & missions: Participation unlocks seats in Enterprise Europe Network, EIT KICs, Vanguard Initiative and S3 Thematic Platforms, multiplying matchmaking and technology-licensing opportunities.

Talent & skills mobility: Interregional pilots support staff secondments and joint training, leveraging Erasmus+, Digital Europe and ESF+ up-/re-skilling schemes.


6. Funding Synergies & Leverage Potential

Blending with Cohesion Funds: I3 can cover the risky demonstration phase (TRL 6-8), while regional ERDF/Just Transition Fund finance large-scale deployment.

Cascade funding (FSTP): SMEs in non-beneficiary regions can still receive micro-grants, widening outreach without extra administrative burden.

Access-to-finance pipelines:

• EIB InnovFin / InvestEU thematic windows for scale-up loans

• European Innovation Council (EIC) Accelerator for follow-on equity

• Local venture capital crowd-in via InvestEU Portal visibility


7. Scale, Replicability & Long-Term Impact

Investment portfolio logic: Multiple sub-projects de-risk technology packages that can be replicated in other EU regions post-grant.

Market entry proof: Demonstrations in varied regulatory and linguistic contexts validate solutions for continent-wide roll-out, improving bankability.

Cohesion dividend: By mandating LDR/TR inclusion, the scheme narrows the innovation gap, fostering wider consumer acceptance and political support.


8. Strategic Benefits over National-Only Funding

Larger addressable market & risk diversification

Shared infrastructure, lowering CAPEX per region

EU branding & credibility when seeking private investment

Eligibility for pan-EU intellectual property protection schemes (unitary patent, EUIPO SME Fund)


9. Actionable Recommendations for Applicants

1. Map complementary S3 priority areas and create a balanced consortium with at least 3 Member States, ensuring >50 % budget benefits LDR/TR partners.

2. Design a clear exploitation plan linking I3 outcomes to future InvestEU or Innovation Fund financing rounds.

3. Embed standardisation work packages to influence CEN-CENELEC deliverables, reinforcing first-mover advantage.

4. Leverage cascade funding to engage additional SMEs and DIHs, expanding impact without amending the Grant Agreement.

5. Align KPIs with EU policy targets (Fit-for-55, Digital Decade, Industrial Alliance roadmaps) to maximise scoring under the ‘Impact’ criterion.


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Bottom line: The I3-2025-INV2a call offers a uniquely European springboard—from prototype to commercial roll-out—by combining interregional cohesion, value-chain integration and alignment with EU strategic agendas. Consortia that harness these EU-wide advantages can achieve faster market penetration, larger scale and stronger investment leverage than any purely national scheme could deliver.

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